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And so it turns out, and impressively so as recently reported in The Lancet, with a substantial attenuation in the frequency and severity of symptoms and improvement in the quality of life.

In a similar vein, Dr Richard Appleton of Alder Hey Children’s Hospital in Liverpool describes a comparable “breakthrough” for the sleep problems – difficulty in falling asleep, waking up during the night – that so often afflict children with neurodevelopmental disorders and which can make life so very difficult for those caring for them.

There is, by contrast, no substitute for the sort of imaginative lateral thinking that has recently resulted in a breakthrough in the treatment of the debilitating chronic cough that can be a feature of so many different conditions – including irritation and injury to the airways, nerve-induced inflammation or throat sensitivity.

The logical approach in such situations could be to seek to modify the factors giving rise to the cough.

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